Solid state characterisation and taste masking efficiency evaluation of polymer based extrudates of isoniazid for paediatric administration
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چکیده
منابع مشابه
Solid state characterisation and taste masking efficiency evaluation of polymer based extrudates of isoniazid for paediatric administration.
Hot melt extrusion has gained considerable attention as a novel technique for taste masking of bitter APIs. The aim of this study was to investigate whether hot melt extrusion could be used to develop taste masked formulations of isoniazid and also to evaluate and correlate different taste assessment methods Two polymers with different physico-chemical properties, Soluplus and Eudragit E-PO wer...
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Orally Disintegrating Tablets (ODT) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. We focused on taste masking and formulation of ranitidine ODT which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2018
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2017.07.008